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The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.

Touch domes in human skin are complex sensory structures not directly linked to hair.

Human hair keratin genes hHa2 and hHb1 are located on chromosomes 17 and 12.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Vitamin D receptor helps control hair growth genes in skin cells.

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.

Too much Sonic Hedgehog protein stops hair growth in embryos.

Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.

CD73 may regulate hair growth and could be targeted for hair growth treatments.

EZH1 and EZH2 are crucial for healthy hair growth and skin repair.

DcR3 helps heal wounds and regrow hair by changing macrophages to a repair-focused type.

Lhx2 helps retinal cells respond to signals for eye development.

HLD10 can include increased body hair and Mongolian spots.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.

The HR protein's role as a repressor is essential for controlling hair growth.

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.