research Evolution in action: highlighting a role for the Agouti gene in development?
The Agouti gene influences pigmentation and may have a developmental role in deer mice.
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research Causal Link of Distinct Mental Disorders with Androgenetic Alopecia and Alopecia Areata: A Bidirectional Two-Sample Mendelian Randomization Study
Major depression disorder increases the risk of alopecia areata, and vice versa.
research Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair
High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
research Picking a Side: Preferential Laterality in Scalp Hair Density
Some people grow more hair on one side of their scalp, possibly due to genetics, behavior, or environment.
research Identification of factors contributing to phenotypic divergence via quantitative image analyses of autosomal recessive woolly hair/hypotrichosis with homozygous c.736T>ALIPH mutation
Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.
research An isolated, implausibly large effect in a case-control study of digit ratio (2D:4D) and male androgenetic alopecia: Comment on Unal (J Cosmet Dermatol 2018;17(3):545-548)
Digit ratio likely doesn't predict male hair loss.
research Cross-species amplification of human microsatellite markers in pig-tailed and stump-tailed macaques
Some human genetic markers work for genetic studies in pig-tailed and stump-tailed macaques, which can help in their conservation.
research Is alopecia areata one of the atopic diseases? A two‐sample Mendelian randomization analysis
Alopecia areata may be linked to atopic diseases like eczema, asthma, and allergies.
research 2P546 Structural Analysis of Curly and Straight Human Hair Fibers by Scanning Microbeam SAXS(52. Bio-imaging,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
Curly and straight hair differ in how their internal fibers are arranged.
research Association between non-scarring alopecia and hypothyroidism: a bidirectional two-sample Mendelian randomization study
The study found that alopecia areata and hypothyroidism increase the risk of each other, but androgenetic alopecia and hypothyroidism do not.
research Efficacy comparison of monotherapies and combination therapies for androgenetic alopecia: A Bayesian networkmeta‐analysis
Combination therapies are more effective for treating androgenetic alopecia than single treatments.
research Histopathologic Findings of Cutaneous Hyperpigmentation in Addison Disease and Immunostain of the Melanocytic Population
The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
research Six SNPs and a TTG indel in sheep desmoglein 4 gene are in complete linkage disequilibrium
Seven genetic variations in sheep's DSG4 gene are linked and affect wool traits.
research Closing the AI generalization gap by adjusting for dermatology condition distribution differences across clinical settings
Adjusting AI training data for skin condition distribution improves accuracy across different clinical settings.
research Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness
A gene called HDAC9 might be a new factor in male-pattern baldness.
research Patients with profuse hair shedding may reveal anagen hair dystrophy: a diagnostic clue of alopecia areata incognita
Some people with heavy hair shedding might actually have a hidden form of alopecia, which can be identified by specific hair changes.
research Soluble factors from human hair papilla cells and dermal fibroblasts dramatically increase the clonal growth of outer root sheath cells
research The pathogenesis model research of alopecia areata: from animal experiments to mathematical prediction models
Animal and mathematical models help understand and develop treatments for alopecia areata.
research Hair as Displacement Record and Social Token: The Shaft as Temporal Archive, Natural Hair as S0_appearance, and Modification as Signal Displacement
Natural hair reflects identity and history, while modifications signal social pressures.
research Generative Artificial Intelligence Tools: Evaluating Ways to Automate Your SALT (GATEWAYS) Scoring of Alopecia Areata
Generative AI tools like GPT-4o can effectively automate SALT scoring for alopecia areata, matching clinician accuracy.
research The genetics of alopecia areata
Alopecia areata has a complex genetic basis that was not fully understood as of 2001.
research Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics
Pangenome analysis reveals key genes for pig adaptation and traits, aiding genetic improvement.
research Editor's evaluation: Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research Where Truth Lies in Advertising
Advertising mixes truth and imagination to persuade consumers that products are essential.
research Molecular modeling and structural characterization of a high glycine–tyrosine hair keratin associated protein
The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
research Filaggrin mutations as an archetype for understanding the pathophysiology of atopic dermatitis
Filaggrin mutations are linked to atopic dermatitis and help explain how genetics and environment affect the disease.
research Multi-ancestry tandem repeat association study of hair colour using exome-wide sequencing
Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
research Additive Effects of Platelet-Rich Plasma and Systemic Therapies in Androgenetic Alopecia: A Retrospective Study
Combining PRP with other treatments may improve hair growth more than PRP alone.
research Improved Hidden Markov Algorithm Based on Bayes in Low Dose CT Images
The improved algorithm enhances low-dose CT image quality significantly better than other methods.
research Association between genetically predicted rheumatoid arthritis and alopecia areata: a two-sample Mendelian randomization study
People with rheumatoid arthritis have a higher risk of developing alopecia areata.