research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.
Leuprolide plus estrogen is more effective than oral contraceptives for reducing hirsutism.
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research Hair loss and Hedgehog inhibitors: a class effect?
Hedgehog pathway inhibitors used for skin cancer can cause significant hair loss, which may improve after stopping the medication.
research 5048 A Rare Cause of Hyperandrogenism in Postmenopausal Women: Ovarian Stromal Hyperplasia
Ovarian stromal hyperplasia can cause high testosterone in postmenopausal women and is treated by removing the ovaries.
research 4 Anti-androgens in gynaecological practice
Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
research Topical Finasteride Therapy in Hirsutism
Topical finasteride may help treat facial hirsutism in women.
research Hidradenitis suppurativa
Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
research インタビュー 内井乃生夫人に聞く 宮崎台ビレジに見る建築家内井昭蔵の姿勢 (39年の時を経た名建築に住む 宮崎台ビレジ--設計=内井昭蔵建築設計事務所)
Androgens reduce macrophage receptor expression, affecting immune response, while antiandrogens counteract this effect.
research Hidradenitis suppurativa secondary to treatment with a gamma secretase inhibitor
A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.
research Hirsutes II: Treatment
The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.
research The selective androgen receptor modulator GTx‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double‐blind, placebo‐controlled phase II trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity
CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.
research 215. Plasma testosterone and dihydrotestosterone in cryptorchid boys treated with HCG
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Testosterone, 17 Ks, 17 beta E2 FSH-LH variations and hirsutism modifications during spironolactone therapy.
Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines
Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1
Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
research Abstract 14
A 15-year-old girl with rare reproductive disorders received hormone therapy to develop secondary sexual traits, but infertility persisted.
research Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors
3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
research Steroid plant hormones: Effects outside plant kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research Androgenisierung
The document concludes that proper diagnosis and individualized treatment are crucial for managing androgenization in women effectively.
research Slow progress in prostate cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
research THE EFFECT OF SPIRONOLACTONE ON HIRSUTISM AND FEMALE ANDROGEN METABOLISM
Spironolactone may help reduce hair growth and testosterone levels in some women with hirsutism.
research Hormonal Therapies for Individuals with Intersex Conditions
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects
Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
research 황금(黃芩)이 전립선비대증(前立腺肥大症) Rat에 미치는 영향
Scutellaria baicalensis may help treat benign prostatic hyperplasia.