research Highlights from JAAD Reviews: August 2025—Bicalutamide for female hair loss
Bicalutamide shows promise for treating female hair loss.
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600-630 / 1000+ resultsresearch Treatment of Hirsutism with a Gonadotropin-Releasing Hormone Agonist (Nafarelin)∗
Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.
research Bicalutamide: A potential new oral antiandrogenic drug for female pattern hair loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research The Role of Probiotics and Synbiotics on Hirsutism
Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
research Control of testosterone 5alpha-reductase activity in the human hyperplastic prostate
Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
research Synergistic Protective Effect of Finasteride and Black Soybean Extract against Dihydrotestosterone-Induced Damage in Human Follicle Dermal Papilla Cells
Combining finasteride and black soybean extract better protects hair cells from damage and may treat hair loss effectively with fewer side effects.
research Bicalutamide does not raise transaminases in comparison to alternative anti-androgen regimens among transfeminine adolescents and young adults: a retrospective cohort study
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
research Bilateral ovarian steroid cell tumor in a postmenopausal woman with progressive hyperandrogenism
Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research Safflower oil body nanoparticles deliver hFGF10 to hair follicles and reduce microinflammation to accelerate hair regeneration in androgenetic alopecia
Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.
research 26-SNP Panel Aids Guiding Androgenetic Alopecia Therapy and Provides Insight into Mechanisms of Action
Genetic profiling can improve androgenetic alopecia treatment by predicting drug response and minimizing side effects.
research 215. Plasma testosterone and dihydrotestosterone in cryptorchid boys treated with HCG
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives.
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research New Methods of Endocrine Management of Prostatic Cancer
New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.
research Finasteride/spironolactone
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Effects of Gonadal Steroids on Melanocytes in Developing Hamsters
Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
research Clinical efficacy and safety of low‐dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research 423 Short-Acting Intramuscular Testosterone Delivered in the Clinic Setting Remains a Key Patient-Friendly and Patient-Directed Option in the Contemporary Management of Hypogonadism
Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.
research Mesotherapy with bicalutamide for female pattern hair loss
Mesotherapy with bicalutamide has limited effectiveness for female hair loss.
research The influence of secoisolariciresinol diglusoside on non-emasculated rat in BPH
SDG helps reduce BPH effects in rats.
research 황금(黃芩)이 전립선비대증(前立腺肥大症) Rat에 미치는 영향
Scutellaria baicalensis may help treat benign prostatic hyperplasia.
research Spironolactone is an effective and well tolerated systemic anti-androgen therapy for hirsute women
Spironolactone effectively reduces unwanted hair growth in women with hirsutism.
research An evaluation of the available pharmacotherapy for the treatment of hirsutism
Birth control pills and antiandrogens are the most effective medicines for excessive body hair in women, but combining them with other treatments and psychological support is best.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research Symptoms of hypogonadism caused by 5α-reductase inhibitors
A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research Idiopathic hypogonadotropic hypogonadism in a male runner is reversed by clomiphene citrate
Clomiphene citrate can reverse low hormone levels and symptoms in male runners with hypogonadotropic hypogonadism.
research Treatment of Lipodystrophy with Troglitazone
Troglitazone increases subcutaneous fat in lipodystrophy patients.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.