56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
54 citations
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June 2015 in “Australasian Journal of Dermatology” Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
54 citations
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February 1986 in “Archives of Dermatology” Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.
53 citations
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October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
51 citations
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October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
50 citations
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March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
50 citations
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January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
50 citations
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May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
50 citations
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July 1996 in “Fertility and Sterility” Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
49 citations
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March 2014 in “Dermatologic clinics” These skin conditions in African men need combined medical treatments and lifestyle changes.
47 citations
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
47 citations
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October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
45 citations
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September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
44 citations
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April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
44 citations
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March 2016 in “Frontiers in cellular neuroscience” Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
42 citations
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January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
41 citations
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March 2007 in “Steroids” New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
39 citations
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January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
38 citations
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February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
38 citations
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February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
36 citations
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August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
36 citations
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February 2004 in “International Journal of Dermatology” Different sports can cause specific skin conditions that need proper diagnosis and treatment.
35 citations
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May 2015 in “Thrombosis Research” Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
35 citations
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March 2005 in “Journal of Investigative Dermatology” Potassium channel openers like minoxidil help hair grow by acting on hair follicles.
35 citations
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August 2004 in “Epilepsy & behavior” Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
34 citations
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October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
34 citations
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July 2011 in “International journal of pharmaceutics” Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
34 citations
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February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.