Newer retinoid drugs are effective for skin conditions but have significant side effects.
May 1987 in “Inpharma (Balgowlah)” Topical minoxidil may slow hair loss but often doesn't lead to satisfactory hair regrowth and requires ongoing treatment.
February 1976 in “PubMed” Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.
2152 citations
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November 2013 in “Urologia Internationalis” Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.
294 citations
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February 1994 in “PubMed” Valproic acid is an effective and safe first-choice treatment for many types of seizures.
235 citations
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September 2004 in “The Journal of urology/The journal of urology” Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.
187 citations
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June 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats frontal hair loss with few side effects.
146 citations
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July 2003 in “Journal of the American Academy of Dermatology” Clobetasol propionate ointment can help some people with total hair loss regrow hair.
122 citations
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March 2013 in “Expert opinion on drug delivery” Optimizing drug delivery to hair follicles is crucial for effective treatment.
100 citations
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September 2016 in “Clinical transplantation/Clinical transplantation.” Voriconazole can cause serious side effects, especially in long-term use.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
56 citations
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January 2004 in “Dermatology” Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.
54 citations
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April 2011 in “Journal of Multidisciplinary Healthcare” SLE patients often face depression and anxiety due to physical changes, with African-American and Hispanic patients having higher unmet psychological needs.
52 citations
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February 1985 in “Archives of Dermatology” Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
51 citations
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April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
46 citations
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May 2009 in “Maturitas” Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
42 citations
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January 2008 in “Clinical colorectal cancer” Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.
42 citations
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January 2007 in “Pediatric dermatology” Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.
35 citations
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January 2002 in “Dermatology” A woman's hair loss during treatment with specific hepatitis C drugs grew back after stopping the medication.
32 citations
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May 2016 in “European journal of dermatology/EJD. European journal of dermatology” Targeted therapies for advanced skin cancer often cause hair and nail problems, which need managing to avoid changing the treatment dose.
30 citations
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February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
27 citations
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August 2010 in “Clinics in Dermatology” Hepatitis C virus can cause skin diseases and dermatologists play a crucial role in identifying these conditions.
23 citations
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April 1991 in “Journal of The American Academy of Dermatology” Minoxidil solution can cause skin irritation and allergies in some users.
21 citations
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July 2011 in “Journal of the American Academy of Dermatology” A man developed a rash similar to pityriasis rubra pilaris after starting sorafenib for cancer, possibly due to the drug's effect on skin cells.
19 citations
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October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
18 citations
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April 2013 in “Inflammatory Bowel Diseases” People with Inflammatory Bowel Disease often lose hair due to stress, medication side effects, or lack of nutrients, and treatment depends on the specific cause.
17 citations
,
June 2020 in “British Journal of Dermatology” Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.
16 citations
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February 2019 in “Pediatric Blood & Cancer” Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.
16 citations
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March 2006 in “The American journal of psychiatry” Lowering the dose of ziprasidone can cause sudden restlessness and urge to move in patients.
16 citations
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July 1988 in “International Journal of Dermatology” The 2% minoxidil solution is safe and effective for treating male pattern baldness.