research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
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480-510 / 1000+ results research Prior bleaching of virgin or colored hair has minimal impact on SERS ‐based hair dye identification
Bleaching hair doesn't affect the accuracy of dye identification using SERS.
research Hair
Hair analysis can detect drug use but is costly and interpretation is complex.
research Refatting rate of human hair lipids after exposure to selenium disulphide detergents
Selenium disulphide detergents increase hair oiliness by boosting some lipids and reducing fatty acids.
research Assessment of styling performance in hair gels and hair sprays by means of a new two-point stiffness test.
The new stiffness test works well for gels but not for sprays.
research Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers
Improved Finasteride delivery for hair loss treatment.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens)
The assay effectively detects hormonal activity of certain chemicals.
research Hair transparency decoding in Asia: From stylists’ perception to in vitro measurement
Higher hair luminosity and shine mean higher perceived transparency.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research Determination of topically applied finasteride penetrated into hair follicles by using the differential stripping technique
research Quantitative Bestimmung von kosmetischen Wirk- und Pflegesubstanzen auf dem Haar
Active agents mainly stay on the hair surface after short washes.
research DEVELOPING AND VALIDATING AN HPLC METHOD TO QUANTIFY SIMULTANEOUSLY DUTASTERIDE AND THEIR RELATED MOLECULES (DUTASTERIDE ACID, 2,5 BIS- (TRI FLUORO METHYL)-ANILINE AND DUTASTERIDE 17 α-EPIMER) IN CAPSULES
A reliable method was created to measure dutasteride and related molecules in capsules.
research Optimization of finasteride nano-emulsion preparation by using chemometrics approaches (and/or Box-Behnken design and regresion model)
research Ex-vivo measurement of scalp follicular infundibulum delivery of zinc pyrithione and climbazole from an anti-dandruff shampoo
The method shows that zinc pyrithione and climbazole from anti-dandruff shampoo effectively reach the scalp.
research Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination
The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Spectrophotometric and Stability Indicating RP-HPLC-PDA method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Tablet Dosage form
The methods accurately measure Finasteride and Tamsulosin in tablets.
research Original article / Article original External post mortem artefact: a key issue in hair result interpretation
Hair test results can be misleading due to external contamination, so they shouldn't be used alone to assess long-term drug use.
research Picogram determination of finasteride in human plasma and semen by high-performance liquid chromatography with atmospheric-pressure chemical-ionization tandem mass spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research Plan of analysis for the study "Maternal Hair Cortisol Concentration Trajectories throughout Pregnancy and Adverse Childhood Experiences"
research Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity
Keratin peptides in hair might help identify gender and ethnicity.
research Uptake of sulfur-35 in human hair.
Sulfur-35 can be used to track hair growth and past exposure.
research HairSentinel: a time-aware anomaly detection framework for forecasting hairfall trends using temporal fusion transformers
"HairSentinel" accurately detects hairfall trends using simple user data, helping identify health risks early.
research Aspect-Level Drug Reviews Sentiment Analysis Based on Double BiGRU and Knowledge Transfer
A model called PM-DBiGRU was developed for analyzing sentiments in drug reviews, and it performed better than other models, but struggled with complex sentences and situations requiring background knowledge.
research Generative Artificial Intelligence Tools: Evaluating Ways to Automate Your SALT ( GATEWAYS ) Scoring of Alopecia Areata
Generative AI tools can accurately score alopecia areata, reducing subjectivity in evaluations.
research Multi-omics analysis of functional substances and expression verification in cashmere fineness
The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.
research Supplemental material_PM_AGA
research Supplemental material_PM_AGA
research Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders
Hair proteomics could be a useful, non-invasive tool for identifying stress-related disorders.