research [Determination of finasteride in human plasma by HPLC-MS].
The two finasteride formulations are bioequivalent.
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540-570 / 1000+ resultsresearch Quantitative analysis of 34 sex (pro)hormones, conjugates and bioactive oxidation products thereof in human plasma by GC- and LC-MS/MS and systematic investigation of overestimations of analyte concentrations not accounted for by method validation
The method accurately measures sex hormones in human plasma but can have small errors.
research Composite Hydrogel Based on Green Chlorella Polysaccharide–Selenium Nanoparticles for Simultaneous Wound Treatment and pH Monitoring
The hydrogel speeds up wound healing, fights bacteria, reduces inflammation, and monitors pH.
research Determination of finasteride in human plasma by liquid–liquid extraction and high-performance liquid chromatography
Valid method measures finasteride in plasma, simple, fast, and affordable.
research Minoxidil and finasteride determination by innovative high-performance liquid chromatography-ultraviolet approach for stability-indicating analysis
A new method accurately measures minoxidil and finasteride in medicines.
research Development and validation of an UPLC method for determination of content uniformity in low-dose solid drugs products using the design space approach
The method ensures accurate finasteride measurement in low-dose drugs, but variability must be checked for each case.
research The use of auto-antibody testing in the evaluation of interstitial lung disease (ILD) – A practical approach for the pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research A practical guide for the study of human and murine sebaceous glands in situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research Protein Microarrays
Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.
research Biomarkers of selenium status in dogs
Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.
research Manganese-Doped Calcium Silicate Nanowire Composite Hydrogels for Melanoma Treatment and Wound Healing
MCSA hydrogels can effectively treat melanoma and aid wound healing.
research Cover Feature: Electronic Circular Dichroism Imaging (ECD i ) Casts a New Light on the Origin of Solid‐State Chiroptical Properties (Chem. Eur. J. 4/2022)
SR-ECDi helps better understand and map the chiroptical properties of solid chiral materials.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research COMPARAÇÃO ENTRE HPLC E IMUNOTURBIDIMETRIA PARA DOSAGEM DE HEMOGLOBINA GLICADA (A1C) COMO CRITÉRIO DIAGNÓSTICO DE DIABETES MELLITUS
HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
research Development of a FRET-based 3D in vitro breast tumor model and its application in evaluating drug-induced apoptosis
A new 3D breast tumor model helps test drug effects more accurately than traditional methods.
research Development and validation of a reversed-phase HPLC method for simultaneous determination of doxazosin mesylate and finasteride
Created method to measure doxazosin mesylate and finasteride together.
research Determination of finasteride in human plasma by HPLC-MS
The method reliably measures finasteride in human plasma.
research SAT-213 Late Diagnosis of Complete Androgen Insensitivity
A 31-year-old woman was diagnosed with Complete Androgen Insensitivity Syndrome much later than usual, leading to a call for earlier detection and treatment guidelines.
research Chromatographic methods for determination of finasteride and tamsulosin hydrochloride and in presence of finasteride degradation product
Two methods can measure finasteride and tamsulosin hydrochloride; HPLC is more advantageous, while TLC offers better separation.
research Clinical diagnosis of COVID-19: a prompt, feasible, and sensitive diagnostic tool for COVID-19 based on a 1,757-patient cohort (The AndroCoV Clinical Scoring for COVID-19 diagnosis)
The study concludes that the new clinical scoring system is a quick, low-cost, and accurate method for diagnosing COVID-19.
research Metal doped keratin film standard for LA-ICP-MS determination of lead in hair samples
A new method accurately measures lead levels in hair to assess exposure.
research Determination of candesartan in human plasma by HPLC-MS-MS
A reliable method was developed to measure candesartan in human plasma.
research High-content drug screening for rare diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses
Reliable method detects finasteride in human plasma at low doses.
research In vitro 3D organotypic hair follicle-model for high-throughput substance testing
The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.
research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization
Chemistry42 effectively creates and optimizes new molecules for drug discovery.
research Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling
Strontium zinc silicate may help treat osteoporosis and muscle loss.
research Enzyme‐Instructed Self‐Assembly for Cellular Supramolecular Chemistry
EISA uses enzymes to create precise nanostructures in cells, offering new ways to design adaptive materials and therapies.
research Queries and Minor Notes
The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.
research Sensitive bromatometric assay methods for finasteride in pharmaceuticals
Three methods accurately measure finasteride in tablets using dyes and bromate-bromide.