research The structure of the “amorphous” matrix of keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
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research Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration
TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
research Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle
Thyroxine can adjust the body's peripheral clock, potentially helping treat clock-related diseases.
research Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice
Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
research Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Responses of hair follicle–associated structures to loss of planar cell polarity signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Genetic Fate Mapping Using Site-Specific Recombinases
The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
research Androgen treatment of postmenopausal women
Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
research Protein disulphide isomerase-mediated grafting of cysteine-containing peptides onto over-bleached hair
PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
research Managing Polycystic Ovary Syndrome: A Cognitive Behavioral Strategy
Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
research Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein
Psoriasis patients' immune response to a hair protein depends on their specific gene type.
research The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen
Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
research Injectable self-healing ceria-based nanocomposite hydrogel with ROS-scavenging activity for skin wound repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research The role of R-spondins and their receptors in bone metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration
Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
research A missing piece: the spiny mouse and the puzzle of menstruating species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Local structure of human hair spatially resolved by sub-micron X-ray beam
Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
research Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep
Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway
VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
research Epithelial Cells in the Hair Follicle Bulge do not Contribute to Epidermal Regeneration after Glucocorticoid-Induced Cutaneous Atrophy
Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
research Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Hair Cosmetics: Dyes
Hair dyes can change hair color temporarily or permanently but may cause side effects like skin reactions and hair damage.
research Microimaging of hairless rat skin by magnetic resonance at 900 MHz
MRI can effectively image skin structures noninvasively.
research Disease Versus Disease: How One Disease May Ameliorate Another
Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.