31 citations
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January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
30 citations
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April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
28 citations
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January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
24 citations
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February 2015 in “Experimental Cell Research” NFIC helps human dental stem cells grow and become tooth-like cells.
19 citations
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January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
15 citations
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April 2001 in “Journal of Dermatological Science” KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
11 citations
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August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
11 citations
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September 2012 in “Journal of Nanjing Medical University” Cyclosporine A was found to increase hair growth in mouse whisker follicles.
8 citations
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May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
8 citations
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February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
4 citations
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May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
2 citations
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March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
1 citations
,
May 2026 in “Nature Communications” CD19-CAR T cell therapy may help regenerate skin in systemic sclerosis.
1 citations
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May 2022 in “Frontiers in medicine” Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
1 citations
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January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
1 citations
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April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
1 citations
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September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
June 2026 in “Research Square” THBS4 helps hair grow by activating hair follicle stem cells.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
February 2026 in “American Journal of Clinical Dermatology” Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.
January 2020 in “Research Portal Denmark” A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
396 citations
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May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
223 citations
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January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
27 citations
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September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.