26 citations
,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
14 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” Formulation P-08-016 better targets hair follicles for baldness treatment.
14 citations
,
February 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
12 citations
,
July 2017 in “Scientific reports” Researchers developed a way to study human body clocks using hair tissue, which works similarly in both healthy and dementia patients.
11 citations
,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
8 citations
,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
7 citations
,
September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
6 citations
,
March 1999 in “Journal of pediatric health care” The document emphasizes the need for primary care providers to understand and care for African American children's hair and skin to boost their self-esteem.
5 citations
,
September 2012 in “Springer eBooks” Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
4 citations
,
January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
1 citations
,
January 2001 in “Cosmetics and toiletries” Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
January 2008 in “Durham e-Theses (Durham University)” Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
April 2019 in “Journal of emerging technologies and innovative research” Early treatment of Female Pattern Hair Loss is important to stop it from getting worse, and various treatments can help, especially in mild to moderate cases.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
305 citations
,
June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
3 citations
,
July 2011 in “Folia Histochemica et Cytobiologica” Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
100 citations
,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
1113 citations
,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
242 citations
,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
209 citations
,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.