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Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Drugs that block GSK-3 show promise for treating various diseases.

Researchers found 15 new genetic links to skin traits in Japanese women.

Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Slug (Snai2) helps regulate hair growth timing in mice.

Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.

A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.

Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.

Circ 0020938 slows down hair growth in cashmere goats.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

SOX4 is crucial for the development of melanoma.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

S-Methylmethionine sulfonium can protect skin from UVB damage.

Lower TGFß1 levels help stem cells become beige fat cells.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

High TSPEAR levels in colorectal cancer predict worse outcomes.

High TSPEAR levels in colorectal cancer predict worse outcomes.

Astrotactin2 affects hair follicle orientation and skin cell polarity.

Foxn1 gene regulation is crucial for thymus development but not for hair growth.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

SQSTM1 gene issues may increase the risk of alopecia areata.

TGFβ signaling prevents sebaceous gland cells from producing fats.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.