June 2019 in “Stem Cell Research” Scientists created MUSIi010-A, a stem cell line from a balding man's scalp, to study hair loss and develop potential treatments.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
18 citations
,
February 1992 in “Molecular Biology Reports” A specific type II hair keratin was identified and found in hair cortex and tongue cells.
13 citations
,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
19 citations
,
March 2003 in “Journal of Investigative Dermatology” Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
January 2023 in “Sovremennye problemy nauki i obrazovaniâ” Miliacin may help prevent hair loss and improve hair growth in mice with a condition similar to human baldness.
December 2025 in “ILDS-DEV”
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” KLF4 is important for keeping hair follicle stem cells inactive.
69 citations
,
February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
24 citations
,
October 2022 in “Cell Regeneration” A new mouse model effectively mimics vitiligo for research and drug testing.
9 citations
,
November 2019 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
11 citations
,
November 1991 in “Journal of Neuropathology & Experimental Neurology” Brindled mice show abnormal catecholamine neuron development due to copper deficiency.
137 citations
,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
January 2005 in “Medical Entomology and Zoology” The reinforced collagen sponge helps grow normal hair in mice.
35 citations
,
November 2019 in “Scientific Reports” Shikimic acid promotes hair growth.
31 citations
,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
6 citations
,
November 2018 in “American journal of transplantation” UV light helped human hair transplants survive in mice without broad immunosuppression.
60 citations
,
February 1992 in “British Journal of Dermatology” Serum from alopecia patients does not stop hair growth in grafted skin on mice.
Understanding hair follicle communication can help treat hair loss.
April 2012 in “한국생물공학회 학술대회”
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” The Lanyu pig's hair follicles are similar to human ones, making it useful for studying skin healing.
50 citations
,
February 2016 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.
8 citations
,
December 2003 in “Experimental Dermatology” Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.
7 citations
,
January 1971 in “Archives of Dermatological Research” January 2006 in “Basic & Clinical Medicine” Hair keratin doesn't significantly affect rat organ function but may help detect early rejection through blood changes.
35 citations
,
January 1990 in “PubMed” Cyclosporin A boosts hair growth in nude mice, but minoxidil does not.
3 citations
,
March 2010 in “Dermatologica Sinica” A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
28 citations
,
December 1997 in “Journal of Biological Chemistry” A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
July 2025 in “Journal of Investigative Dermatology” Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.