22 citations
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February 2008 in “Journal of Dermatological Science” EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
555 citations
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July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
156 citations
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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
151 citations
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November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
56 citations
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February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
35 citations
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January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
32 citations
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February 2008 in “Developmental dynamics” Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
30 citations
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April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
December 2023 in “Biological & pharmaceutical bulletin” IPM enhances skin penetration of hydrophilic drugs.
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
68 citations
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September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
43 citations
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January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
228 citations
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September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
27 citations
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March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
11 citations
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March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
211 citations
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October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
12 citations
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June 2016 in “Reviews in Endocrine and Metabolic Disorders” Some skin diseases and their treatments can negatively affect male fertility.
September 2018 in “Journal of Investigative Dermatology” Non-white organ transplant patients have worse skin cancer outcomes due to later diagnosis and treatment.
49 citations
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December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
April 2025 in “International Journal of Research in Dermatology” Thyroid disorders are linked to skin issues and autoimmune skin diseases.
March 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” Certain plants like Aloe vera and Neem are effective and safe for treating various skin conditions.
19 citations
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January 2000 in “Biological and Pharmaceutical Bulletin” Diclofenac salt delivery through skin varies based on the salt's counterions.
112 citations
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
21 citations
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November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
2 citations
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November 2025 in “Frontiers in Immunology” Females are more affected by immune-related skin diseases, needing targeted health interventions.
January 2025 in “ARC Journal of Dermatology” Vaping may harm skin health by causing inflammation.
71 citations
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January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
59 citations
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March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.