2 citations
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November 2015 in “Actas Dermo-Sifiliográficas” The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
252 citations
,
February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
4 citations
,
May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
1 citations
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May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
January 2008 in “Durham e-Theses (Durham University)” Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
75 citations
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March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
22 citations
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June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
13 citations
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January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
January 2018 in “Open access journal of pharmaceutical research” Biofield Energy Healing may increase hair growth by enhancing cell proliferation.
96 citations
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October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
33 citations
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September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
29 citations
,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
6 citations
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August 2007 in “Journal of Surgical Research” Mice genetically modified to produce more Del1 protein had faster hair regrowth.
December 2025 in “Philippine Journal of Internal Medicine” Early recognition and tailored treatment are crucial for managing overlapping systemic lupus erythematosus and systemic sclerosis.
2 citations
,
January 2016 in “US Endocrinology” Scalp hair thinning in women with PCOS is linked to metabolic issues like abnormal glucose tolerance, high LDL, and skipped meals.
June 2025 in “British Journal of Dermatology” A rare skin condition in a boy is likely due to a specific genetic mutation pattern.
31 citations
,
July 2012 in “Journal of Lipid Research” ACBP is crucial for healthy skin in mice.
92 citations
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March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
18 citations
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January 2013 in “Journal of Investigative Dermatology” WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.
Skin stem cells in hair follicles are important for touch sensation.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
81 citations
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March 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered scaffolds help heal skin wounds, but perfect treatments are still needed.
170 citations
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November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
23 citations
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November 2018 in “npj Regenerative Medicine” Healing of heart and skin wounds in animals are similar.
15 citations
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March 2024 in “Journal of Clinical Medicine” Selumetinib causes skin and hair side effects in kids with NF1, affecting treatment and quality of life.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
101 citations
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October 2007 in “Journal of Biological Chemistry” Reduced matriptase activity causes skin and hair issues in both humans and mice.