23 citations
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June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
23 citations
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July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
23 citations
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December 2001 in “Lasers in Surgery and Medicine” Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
19 citations
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April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
19 citations
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November 1993 in “Mammalian Genome” A gene mutation in mice causes permanent hair loss and skin issues.
17 citations
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September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
17 citations
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February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
16 citations
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October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
16 citations
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March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
16 citations
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September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
15 citations
,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
13 citations
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January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
13 citations
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September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
13 citations
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July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
12 citations
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November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
12 citations
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January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
12 citations
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December 2010 in “Burns” P-auricular skin is the best donor site for high stem cell content in keratinocyte cultures.
11 citations
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January 2023 in “BioMed Research International” Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
10 citations
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December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
9 citations
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
8 citations
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October 2019 in “The Journal of surgical research/Journal of surgical research” Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
8 citations
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January 2013 in “The scientific world journal/TheScientificWorldjournal” Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
7 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
7 citations
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June 2024 in “Communications Medicine” Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
7 citations
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August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
7 citations
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August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
7 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
7 citations
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February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
7 citations
,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.