12 citations
,
June 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
3 citations
,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
2 citations
,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
128 citations
,
August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
76 citations
,
February 2007 in “Cancer Research” Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.
37 citations
,
January 2022 in “Frontiers in Genetics” Aging reduces dermal sheath cells, affecting youthful skin appearance.
36 citations
,
March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
18 citations
,
October 2014 in “In vitro cellular & developmental biology. Animal” Hair follicle stem cells can become neural cells using different methods, with varying efficiency.
16 citations
,
January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
1 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
April 2016 in “Journal of Investigative Dermatology” Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
1 citations
,
November 2022 in “Frontiers in medicine” The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
September 2022 in “Dermatology and therapy” Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
3 citations
,
November 2021 in “Frontiers in Genetics” Certain genes are linked to the quality of cashmere in goats.
2 citations
,
August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
March 2026 in “Plastic and Aesthetic Research” Adipose-derived stem cell exosomes can help reduce skin aging from UV exposure.
February 2026 in “Nature Communications” A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
59 citations
,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
21 citations
,
January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
16 citations
,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
11 citations
,
January 2017 in “Oxidative medicine and cellular longevity” Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.