Loss of the p53 gene alone causes tumors, and losing both p53 and Rb genes speeds up aggressive skin cancer.
Loss of the p53 gene alone causes tumors, and losing both p53 and Rb genes speeds up aggressive skin cancer.
RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
3D models from confocal microscopy improve melanoma detection on sun-damaged skin.
2 citations
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August 2020 in “Natural Product Communications” A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.
1 citations
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January 2023 in “International journal of molecular sciences” Rabbits with Sarcoptes scabiei had thicker skin, cell death, and skin hardening.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
42 citations
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March 2014 in “European Journal of Pharmacology” Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
27 citations
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December 1997 in “Archives of Dermatological Research” Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
24 citations
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August 2022 in “Immunity” Type 2 immunity helps control mite growth in hair follicles, preventing damage.
65 citations
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June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
36 citations
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October 2019 in “Cell Proliferation” Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.
148 citations
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August 2022 in “Stem Cell Research & Therapy” Encapsulated stem cell exosomes in hydrogel improve wound healing.
23 citations
,
May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
29 citations
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June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
15 citations
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April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
6 citations
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November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
1 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Weak cell junctions disrupt hair follicle stem cell rest.
35 citations
,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
6 citations
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April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
43 citations
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December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
6 citations
,
November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
1 citations
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March 2015 in “PubMed” Vitamin D helps treat psoriasis by promoting skin cell differentiation and reducing growth.
June 2025 in “Indian Journal of Dermatology” A rare skin condition was identified and planned for treatment in an elderly man.
July 2024 in “Journal of Investigative Dermatology” Inhibiting PDE8A may help treat hair loss by boosting fat cell growth and hair regeneration.
September 2011 in “Chinese Journal of Dermatology” A man's skin condition was misdiagnosed and later identified as a rare type of skin cancer, which did not improve with treatment.
January 2014 in “Genes and Cells” Genetically modified cells improved skin wound healing in rats.
19 citations
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April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
10 citations
,
January 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
1 citations
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October 2021 in “Jundishapur Journal of Natural Pharmaceutical Products” Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.