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,
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,
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223 citations
,
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176 citations
,
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158 citations
,
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157 citations
,
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144 citations
,
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143 citations
,
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120 citations
,
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114 citations
,
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113 citations
,
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104 citations
,
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103 citations
,
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99 citations
,
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92 citations
,
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91 citations
,
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91 citations
,
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91 citations
,
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86 citations
,
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82 citations
,
April 2008 in “Journal of Investigative Dermatology” EDA2R gene linked to hair loss.
77 citations
,
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75 citations
,
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69 citations
,
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68 citations
,
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66 citations
,
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65 citations
,
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65 citations
,
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64 citations
,
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60 citations
,
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,
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