2 citations
,
September 2019 in “Dermatologic Surgery” The two-step procedure of fat grafting followed by hair grafting improves scalp and facial scar correction.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
4 citations
,
February 2023 in “International Journal of Stem Cells” The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
4 citations
,
July 2023 in “Experimental Dermatology” Fat grafting reduces scar fibrosis but may slow skin healing.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
25 citations
,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
25 citations
,
June 2013 in “Obesity Reviews” Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
4 citations
,
July 1992 in “Clinics in Dermatology” Skin surgery has significantly advanced since 1950, with improvements in chemical peels, hair restoration, lasers, and Mohs surgery, and the development of less invasive techniques and specialized training.
3 citations
,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
February 2026 in “Veterinary Sciences” SPARC-modified stem cells significantly improve dog skin wound healing.
February 2025 in “Theranostics” 3D bioprinting with special hydrogels can create artificial skin that heals wounds and regrows hair in mice.
March 2022 in “Indian Journal of Animal Research” Dog hair follicle stem cells can turn into fat cells.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
65 citations
,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
January 2025 in “Health engineering.” Combining stem cells and organoids could improve skin regeneration treatments.
December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” Thymosin β4 and VEGF are important for blood vessel formation in many organs.
265 citations
,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
1 citations
,
July 2023 in “Cytotherapy” Magnetic nanovesicles from stem cells can improve hair growth by staying in the skin longer.
February 2026 in “American Journal of Clinical Dermatology” Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
396 citations
,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
133 citations
,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
87 citations
,
February 2004 in “Plastic and Reconstructive Surgery” Hair follicle stem cells helped heal a severe scalp burn without needing traditional skin grafts.