research CUTANEOUS LUPUS ERYTHEMATOSUS – WHAT IS NEW IN 2024?
New treatments and understanding of skin lupus are emerging in 2024.
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research Cutaneous Manifestations of COVID-19: A Brief Review of a Possible Diagnostic Tool
Skin symptoms could help in early COVID-19 diagnosis but more research is needed to confirm their reliability.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration
Macrophages and fibroblasts help repair organs after injury, affecting whether they regenerate or scar.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin
Human hair follicles produce and respond to erythropoietin, helping protect against stress.
research Local heroes or villains: tissue-resident memory T cells in human health and disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research New Aspects of Langerhans' Cell Function
Langerhans cells are crucial for skin immunity and allergic reactions.
research Brachioradial pruritus: Treatment with topical capsaicin
Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
research Wnt signaling: the good and the bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome
Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid‐treated culture of a newborn rat keratinocyte cell line
Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.
research Pattern of tissue invasion by Propionibacterium acnes in acne vulgaris
The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
research Oral syphilis: report of three cases and characterization of the inflammatory cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
research The localisation and characterisation of insulin-like growth factor-I receptors and the investigation of melatonin receptors on the hair follicles of seasonal and non-seasonal fibre-producing goats
Goat hair follicles have insulin-like growth factor-I receptors that might affect hair growth, but no melatonin receptors were found.
research Systemic Lupus Erythematosus
Systemic lupus erythematosus is a chronic disease causing inflammation and various symptoms, mainly in young women, treated with anti-inflammatory and immunosuppressive drugs.
research Feline acne and results of treatment with mupirocin in an open clinical trial: 25 cases (1994–96)
Mupirocin ointment effectively treats feline acne.
research The role of cathepsin E in terminal differentiation of keratinocytes
Cathepsin E is crucial for normal skin cell differentiation and development.
research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
PDCD4 is important for controlling skin cell growth and healing.
research A novel mutation in the FERMT1 gene in a Spanish family with Kindler’s syndrome
Researchers found a new mutation in the FERMT1 gene in a Spanish family with Kindler syndrome.
research Acute localized exanthematous pustulosis due to metronidazole
A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.
research The mineralization of hair follicle tissue
Hair follicle tissue can induce mineral formation, likely due to a potent nucleator.
research Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1
A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.
research Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice
Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.
research Limb tourniquet syndrome - A cautionary tale
An elderly man with dementia suffered limb damage from rubber bands around his leg, highlighting the need for careful monitoring to prevent such injuries.
research Bone marrow-derived vasculogenesis leads to scarless regeneration in deep wounds with periosteal defects
Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
research Isolated Linear Discoid Lupus Erythematosus of Scalp Following Lines of Blaschko
Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.