research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
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research Epithelial Skin Biology
The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
research Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells
Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
research Mechanical forces in skin disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration
Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
research Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber
Changes in keratin make hair follicles stiffer.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease
The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research The regulatory role of the tetrapeptide A cSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role
AcSDKP may help prevent skin and hair aging and promote their growth.
research Keratin
Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
research Structure and Function of the Skin
The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research KERATIN 17-related recessive atypical pachyonychia congenita with variable hair and tooth anomalies
A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.
research Ultrastructural Localization of Hair Keratins in Human Scalp Hair Shafts as Revealed by Rapid-Freezing Immunocytochemistry.
Hair keratins are mainly on macrofibrils in the cortex and in the endocuticle in the cuticle.
research A two-phase model of skin epidermal stratification: lessons from centrosomes
Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Metabolic Syndrome and Skin Manifestations: A Bidirectional Association
Skin conditions can indicate underlying metabolic issues.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Skin, Genetic Defects, and Aging
Genetic defects and UV radiation cause skin damage and aging.
research Mechanisms of Dermatophyte Invasion on New Zealand Rabbit Skin Models
The study found that injecting spores directly into rabbit skin effectively caused fungal skin infections, with symptoms worsening over time.
research Model systems for the study of dermatophyte and non-dermatophyte invasion of human keratin.
Terbinafine effectively stops fungal invasion of human keratin.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research Hormone replacement therapy and the skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Building Epithelial Tissues from Skin Stem Cells
Skin stem cells help maintain skin health, grow hair, and heal wounds.
research Physiological and biological skin changes in pregnancy
Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.