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research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin

555 citations , July 2001 in “Genes & Development”

Tcf3 and Lef1 are key in deciding skin stem cell roles.

research Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing

527 citations , December 2011 in “Proceedings of the National Academy of Sciences”

Dextran hydrogels improve burn wound healing and skin regeneration.

research Advances in skin grafting and treatment of cutaneous wounds

518 citations , November 2014 in “Science”

Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.

research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

499 citations , September 2011 in “Cell”

Fat-related cells are important for initiating hair growth.

research Reversible Activation of c-Myc in Skin

467 citations , May 1999 in “Molecular Cell”

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

441 citations , May 1996 in “Journal of Cell Science”

Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.

research Emerging interactions between skin stem cells and their niches

426 citations , August 2014 in “Nature Medicine”

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

research Hair-bearing human skin generated entirely from pluripotent stem cells

425 citations , June 2020 in “Nature”

Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.

research Skin shedding and tissue regeneration in African spiny mice (Acomys)

418 citations , September 2012 in “Nature”

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

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