1039 citations
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
1 citations
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October 2025 in “International Journal of Nanomedicine” Exosomes could revolutionize skin disease treatment and healing.
1 citations
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September 2023 in “Research Square (Research Square)” The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
306 citations
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April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
150 citations
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April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
67 citations
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January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
49 citations
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May 2020 in “Frontiers in Public Health” Insulin resistance linked to obesity may increase COVID-19 severity.
48 citations
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
43 citations
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July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
39 citations
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March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
37 citations
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
36 citations
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May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
36 citations
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September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
31 citations
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May 2012 in “European Journal of Dermatology” Menopause affects hair and skin; more research needed for treatment.
30 citations
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March 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
25 citations
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November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
24 citations
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June 2018 in “Reviews in endocrine and metabolic disorders” Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
24 citations
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March 2015 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.
22 citations
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November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
22 citations
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July 2024 in “Archives of Plastic Surgery” Injectable skin boosters effectively rejuvenate aging skin by improving hydration and elasticity.
22 citations
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November 2018 in “Brazilian Journal of Pharmaceutical Sciences” New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
21 citations
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February 2015 in “Journal of Feline Medicine and Surgery” Negative pressure wound therapy is effective for skin grafts in cats.