23 citations
,
September 2018 in “Dermatologic Therapy” Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.
9 citations
,
July 2018 in “International Journal of Dermatology” White and yellow dots indicate severe female hair loss in dark skin.
264 citations
,
January 2008 in “Journal of biomedical optics” Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
January 2023 in “Revista da Associação Médica Brasileira” Brazilian patients with inflammatory bowel disease have a high rate of skin problems compared to healthy people.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
158 citations
,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
43 citations
,
January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
28 citations
,
February 2012 in “PLoS ONE” A PKP1 gene mutation causes skin fragility and hair loss in Chesapeake Bay retriever puppies.
13 citations
,
January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
January 2018 in “Springer eBooks” Different races and genders have unique skin and hair issues, requiring specialized care and more research for effective treatment.
86 citations
,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
16 citations
,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
184 citations
,
September 2006 in “PLoS Genetics” The Apc gene is crucial for normal skin and thymus development.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
295 citations
,
March 2016 in “Life Sciences” Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
187 citations
,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
147 citations
,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
103 citations
,
March 2011 in “PLoS Biology” Birds can lose neck feathers due to a genetic change that increases a gene's activity, helping them adapt to heat.
98 citations
,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
71 citations
,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
67 citations
,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
60 citations
,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
54 citations
,
April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
52 citations
,
January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
40 citations
,
April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
31 citations
,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
27 citations
,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.