research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
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960-990 / 1000+ results research Delta‐6 desaturase knockout mouse illustrates previously undocumented pathology
Lack of certain fatty acids causes skin, immune, and fertility issues in mice.
research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect
A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
research Data Sheet 1_The clinical features, muscle pathology, and role of autophagy in anti-Ku-positive patients.docx
Anti-Ku-positive patients often have muscle weakness and autophagy plays a key role in their condition.
research Sound Wave‐Activated Self‐Powered Adhesive Dressing for Accelerated Wound Healing
The dressing speeds up wound healing using sound waves without needing extra devices.
research pH-Responsive Hydrogel with Dual-crosslinked Network of Polyvinyl Alcohol/Boric Acid for Controlled Release of Salvianolic Acid B: Novel Pro-Regenerative Mechanisms in Scar Inhibition and Wound Healing
The hydrogel helps reduce scarring and improve wound healing by releasing salvianolic acid B in acidic conditions.
research Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis
High-concentration cell-free adipose extract reduces scar formation and improves scar appearance.
research Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars
Inflammatory acne damages skin stem cells and reduces their growth, leading to atrophic acne scars.
research 1389 Local injection with anti-herpes simplex virus antibodies protects against development of herpes simplex virus–induced sweating disturbance
Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.
research 546 Epidermal growth factor receptor as a key regulator of the immune privilege
EGFR is crucial for preventing hair follicle inflammation and hair loss.
research Alopecia difusa e atrofia da tireoide associadas à deficiência de selênio e zinco em ovinos.
Selenium and zinc deficiency in sheep leads to thyroid and skin problems.
research 1298 External light activates hair follicle stem cells through eyes via the ipRGC-SCN-sympathetic neural circuit
Light can activate hair growth through a pathway from the eyes to hair follicles.
research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Expansion of specialized epidermis induced by hormonal state and mechanical strain
Nipple area expansion in mice needs both pregnancy hormones and mechanical strain.
research Over-, ectopic-expression of FoxN1 at early life adversely influences lymphopoiesis (HEM3P.280)
Early over-expression of FoxN1 harms immune and skin development.
research Curcumin grafted poly(vinyl alcohol) for ascorbyyl palmitate encapsulation
Encapsulating ascorbyl palmitate in curcumin-grafted particles improves its stability and skin penetration.
research De novo formation and ultra-structural characterization of a fiber-producing human hair follicle equivalent in vitro
Scientists recreated human hair follicles in the lab that can grow hair.
research Chronic toxicity of 3,4,3′,4′-tetrachlorobiphenyl in the marmoset monkey (Callithrix jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.
research Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice*1
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
research The lipide composition of epidermis and dermis of mice undergoing carcinogenesis by methylcholanthrene.
Cholesterol and phospholipids increase in mouse skin during cancer development, with differences between male and female skin.
research Le gènehairlessde la souris
The hairless gene is crucial for hair health, and its mutations cause hair loss.
research UTILIZAÇÃO DOS FIOS ABSORVÍVEIS DE POLIDIOXANONA NO REJUVENESCIMENTO FACIAL
PDO threads improve skin firmness and elasticity with minimal recovery time.
research 837 Micro-regional transcriptome reveals local dermal-epidermal intercorrelation in atopic dermatitis
Atopic dermatitis shows a link between skin layers in inflammation, detectable with detailed gene analysis.
research 322 Upregulation of SERPINB3/B4 and S100A7-9 in hidradenitis suppurativa/acne inversa
Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.
research 奈米級物理性防曬化?菻~之顯微結構分析、皮膚穿透及細胞毒性之研究
Nano-sized sunscreens may penetrate skin and pose toxicity risks.
research Ultrashort peptide nanofibrous hydrogels for the acceleration of healing of burn wounds
Peptide hydrogels heal burn wounds faster and better than standard dressings.
research Sprayable biomimetic double mask with rapid autophasing and hierarchical programming for scarless wound healing
The new sprayable wound mask helps heal wounds without scars.
research TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022
Advancements in skin treatment and wound healing include promising gene therapy, 3D skin models, and potential new therapies.
research Cloning and Activity of Mouse Ultra-High Sulfur Keratin Gene Promoter
The UHS promoter is specific to mouse hair follicles.
research A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds
A wearable patch speeds up healing of chronic wounds by monitoring and treating them.