August 2023 in “Journal of The American Academy of Dermatology” Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.
July 2023 in “JAAD International” Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
May 2022 in “Advances in Cosmetic Surgery” Platelet-rich fibrin helps in healing and rejuvenation but results vary and can take time.
The FUE hair transplant technique provides a natural and satisfying solution for male pattern baldness.
Reducing PIEZO1 speeds up wound healing.
March 2021 in “Research Square (Research Square)” Ketoconazole's structure and dynamics are linked, aiding antifungal drug development.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” 17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.
August 2019 in “Carolina Digital Repository (University of North Carolina at Chapel Hill)” DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.
Understanding hair follicle communication can help treat hair loss.
October 2012 in “Advanced Materials Research” Higher temperatures improve rabbit hair strength up to 50°C, but moisture weakens it.
July 2012 in “American Journal of Clinical Pathology” Hair examination is crucial for diagnosing Netherton syndrome in patients with certain skin symptoms.
April 2012 in “Informa Healthcare eBooks” Senescent alopecia is a type of hair loss that occurs after age 50, not caused by genetics, and involves a gradual thinning of hair without significant inflammation.
Epidermal stem cells help renew skin and heal wounds, influenced by specific proteins and markers.
April 2007 in “Oncology Times” Chemoprevention is rarely used due to concerns about risks, side effects, and lack of clear guidelines.
Finasteride may improve prostate cancer therapy by enhancing testosterone's benefits and reducing risks.
January 2002 in “Basic medical sciences and clinics” Hair follicle stem cells are crucial for hair growth and renewal.
November 2000 in “Current problems in dermatology” New treatments for hair loss and excessive hair growth show promise with few side effects and advancements in laser technology.
Hair loss should be medically treated, as non-medical treatments are ineffective and hair loss can indicate serious health issues.
January 2022 in “International Journal of Health Science” Topical products, especially specific shampoos, are effective in treating androgenetic alopecia by delivering active ingredients to hair follicles and improving hair quality.
January 2000 in “Annals of Dermatology” Finasteride effectively treats hair loss in men with minimal side effects.
520 citations
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February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
329 citations
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January 1997 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.
266 citations
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January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
227 citations
,
January 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
222 citations
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September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
207 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
205 citations
,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
176 citations
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
153 citations
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April 2009 in “Urology” Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.