336 citations
,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
219 citations
,
September 2009 in “European journal of epidemiology” The Rotterdam Study aims to understand various diseases in older adults.
162 citations
,
April 2016 in “The Lancet Diabetes & Endocrinology” Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
156 citations
,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
150 citations
,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
148 citations
,
February 2005 in “Autoimmunity Reviews” Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
100 citations
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July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
65 citations
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September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
64 citations
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August 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
60 citations
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September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
56 citations
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March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
53 citations
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January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
50 citations
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September 2016 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
44 citations
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January 2005 in “Dermatology” Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.
43 citations
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September 2012 in “International Journal of Dermatology” Hormonal therapies are safe and effective for treating adult women's acne.
35 citations
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August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
31 citations
,
January 2019 in “Journal of Cutaneous Medicine and Surgery” Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.
29 citations
,
March 2017 in “International Journal of Women's Dermatology” Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
27 citations
,
September 2014 in “JAMA dermatology” Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.
27 citations
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June 2013 in “Alcoholism: Clinical and Experimental Research” Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.
26 citations
,
October 2023 in “Neuroscience Bulletin” Stem cell therapy could help regenerate inner ear hair cells to treat hearing loss.
25 citations
,
February 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
24 citations
,
May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
22 citations
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September 2015 in “Fertility and Sterility” The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.
19 citations
,
October 2018 in “PLOS ONE” 5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
18 citations
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February 2025 in “Drug Delivery and Translational Research” The microneedle patches effectively treat allergic conjunctivitis with controlled, sustained release of medication.
14 citations
,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
14 citations
,
November 2020 in “International Journal of Biological Macromolecules” Mushroom-based scaffolds help heal skin wounds and regrow hair.
14 citations
,
January 2020 in “Advances in Dermatology and Allergology” Higher interleukin-15 levels are linked to more severe alopecia areata, but not to age or gender.