114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
105 citations
,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
102 citations
,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
91 citations
,
November 2007 in “Archives of Dermatology” Smoking linked to hair loss in Asian men.
66 citations
,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
63 citations
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May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
50 citations
,
November 2010 in “Tissue Engineering Part A” Hair follicle cells and intestinal tissue can create strong, functional blood vessel replacements.
46 citations
,
December 2014 in “Journal of The American Academy of Dermatology” Premature hair graying in young men is linked to family history, obesity, and smoking.
22 citations
,
November 2010 in “Toxicological & Environmental Chemistry Reviews” Smokers and people with dyed hair have higher levels of certain metals in their hair.
21 citations
,
May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
19 citations
,
September 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
16 citations
,
March 2015 in “Clinical Cancer Research” The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
12 citations
,
January 2002 in “Environmental and Molecular Mutagenesis” Smoking reduces antioxidants and causes DNA damage in hair follicles.
8 citations
,
May 2019 in “Journal of dermatological treatment” Vismodegib is effective for basal cell carcinoma but has severe side effects.
7 citations
,
June 2010 in “Bioorganic & medicinal chemistry letters” Two new compounds were found to effectively reduce hair growth in mice.
7 citations
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September 2020 in “Journal of Cosmetic Dermatology” Smoking increases early hair loss risk in men; quitting may help prevent it.
5 citations
,
January 2021 in “Skin appendage disorders” Smoking is linked to more hair loss and premature graying compared to nonsmokers.
4 citations
,
January 2015 in “Dermatology Online Journal” Smoking can cause yellowing of upper lip hair.
3 citations
,
October 2021 in “Cureus” Smoking can cause yellow discoloration of upper lip hair and nails.
2 citations
,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
1 citations
,
August 2012 in “Journal of Emerging Trends in Engineering and Applied Sciences” Smoking and alcohol may cause early hair loss by altering trace elements.
Vismodegib effectively treats advanced basal cell carcinoma but requires careful management of serious side effects.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
The treatment was ineffective in humans.
February 2026 in “South African Journal of Botany” Smoke water helps rice roots grow longer but reduces root hair growth under low phosphorus.
August 2025 in “Tobacco Induced Diseases” Smoking harms skin quality and health, which may encourage quitting.
July 2025 in “Pakistan Journal of Medicine and Dentistry” Smoking increases the risk and severity of male pattern baldness.
October 2024 in “Comprehensive Health and Biomedical Studies” Smoking and alcohol worsen hair transplant results.
September 2024 in “Dermatologica Sinica” Early and accurate diagnosis of congenital smooth muscle hamartomas is crucial to distinguish them from other conditions.