research Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
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research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
research Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Smoothened antagonists for hair inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research A Review on Flaxseed as a Hair Smoothening Agent
Flaxseed can naturally smooth and improve hair health.
research Have the facts on topical minoxidil been smoothed over?
Topical minoxidil may slow hair loss but often doesn't lead to satisfactory hair regrowth and requires ongoing treatment.
research Identification of the cell lineage at the origin of basal cell carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Hedgehog signalling in skin development and cancer
The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.
research Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop
Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
research AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
research The Organizer and Beyond
Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.
research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
research 942 Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
research Effects of vinblastine and its metabolites on nausea and alopecia associated receptors
Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.
research Oncogenes and morphogens: intricacies of targeted therapy in cutaneous basal cell carcinoma
Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.
research Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics
Future hair cosmetics will be safer and more effective.
research Comparative study of instrumental measurement and sensory evaluation methods for the repairing effect of mildly damaged hair bundles
Instrumental methods accurately and conveniently show hair care products repair hair.
research Development of predictive regression model for perceived hair breakage in Indian consumers
The model predicts hair breakage based on key hair properties and helps product developers.
research The Effects of Temperature, pH and Moisture Exposure on Human Hair
High temperatures, acidic conditions, and too much coconut oil damage hair, while a pH of 5 to 7 keeps it healthy.
research ミレットエキス，パントテン酸カルシウム，L—シスチン，ビオチン含有食品の摂取による毛髪密度および頭髪の外観変化の検証試験
The supplement improved hair density and overall hair beauty.
research Deposition of 18-MEA onto Damaged Hair to Form a Persistent Hydrophobicity
18-MEA and SPDA can restore damaged hair's smoothness and reduce frizz.
research Evaluation of a novel hybrid polymer in hair treatment
The new polymer improves dyed hair's color, moisture, shine, and smoothness.
research A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone
A new method improves silicone oil coating on hair, enhancing moisture and lubrication.
research Enhanced substantivity of hyaluronic acid on keratin substrates via polymer complexation
Polymer complexation makes hyaluronic acid stick to hair better, enhancing its moisturizing effects.
research A REVIEW ON HERBAL SHAMPOO AND ITS EVALUATION
Herbal shampoo cleans hair well and is safer than regular shampoos.
research TO FORMULATE A HERBAL HAIR SMOOTHING/STRAIGHTENING CREAM USING NATURAL INGREDIENTS AND EVALUATE ITS EFFECTIVENESS ON HAIR TEXTURE
The herbal cream effectively smooths and straightens hair safely.
research TO FORMULATE A HERBAL HAIR SMOOTHING/STRAIGHTENING CREAM USING NATURAL INGREDIENTS AND EVALUATE ITS EFFECTIVENESS ON HAIR TEXTURE
The herbal cream effectively smooths and straightens hair safely.