11 citations
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August 2024 in “Nature Communications” Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.
11 citations
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June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
11 citations
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August 2012 in “Canadian journal of ophthalmology” Eyelash alopecia areata often goes undiagnosed and can lead to complete eyelash regrowth, especially in younger patients.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
10 citations
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February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
10 citations
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June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
10 citations
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January 2010 in “Veterinary pathology” A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
9 citations
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March 2019 in “Journal of cosmetic dermatology” Different treatments can make an aging upper lip look younger and better proportioned.
9 citations
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August 2013 in “Archives of Dermatological Research” A gene called BMAL1 plays a role in controlling hair growth.
9 citations
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May 2005 in “Expert Review of Clinical Immunology” Blocking interferon-gamma might help treat various autoimmune diseases.
8 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
8 citations
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November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
8 citations
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June 2020 in “The Journal of Clinical Endocrinology and Metabolism” Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
7 citations
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April 2013 in “Journal of Cellular Biochemistry” CD61 is important for mouse tooth cell growth and works through Lgr5.
6 citations
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March 1984 in “British journal of addiction” The Edwardian medical campaign linked maternal drinking to infant mortality and national decline, influencing hygiene education and leading to a ban on children under 14 from pubs.
4 citations
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February 2021 in “International Journal of Dermatology” Prostaglandins may contribute to male hair loss; targeting them could help treat it.
4 citations
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January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
4 citations
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January 2019 in “International journal of molecular sciences” Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
4 citations
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July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
3 citations
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May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
2 citations
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February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
2 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
2 citations
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January 1990 in “Leukemia & Lymphoma” The combination of mitoxantrone, etoposide, and prednisolone is effective for treating relapsed lymphoma with manageable side effects.
1 citations
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February 2024 in “Pharmacognosy Journal” Fenugreek seed extract boosts testosterone and improves male reproductive health without heart side effects.
1 citations
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January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
1 citations
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May 2023 in “Journal of molecular evolution” Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
1 citations
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February 2023 in “Frontiers in Endocrinology” Childhood growth hormone deficiency can be accurately diagnosed using gene expression data and random forest analysis.
1 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
1 citations
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September 2017 in “Textual Practice” The document concludes that Hilary Mantel's memoir shows how childhood experiences affect adult health, criticizing modern medicine for ignoring the mental aspects of physical illness.
1 citations
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April 2016 in “Journal of Reproductive Health and Medicine” Diagnosing new systemic lupus during pregnancy is hard but important for the health of the mother and baby.