research Kin‐cohort analysis of LRRK2‐G2019S penetrance in Parkinson's disease
The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
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research Effects of maintaining solstice light and temperature on reproductive activity, coat growth, plasma prolactin and melatonin in goats
Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.
research Repairing the lungs one breath at a time: How dedicated or facultative are you?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
research Principles and mechanisms of regeneration in the mouse model for wound‐induced hair follicle neogenesis
Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
research A preliminary study of finasteride in Tourette syndrome
Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
research Primary cicatricial alopecia: Recent advances in understanding and management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
Genetic variations affecting skin structure play a key role in severe acne.
research Fat, Stem Cells, and Platelet-Rich Plasma
The conclusion is that fat grafting is safe and effective but carries risks that need careful management.
research Stem cells in embryonic skin development
The origins of many adult skin stem cells are still mostly unknown.
research Nanotechnology-Based Cosmetics for Hair Care
Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
research Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Hirsutism: Diagnosis and management
The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research Studying the genetic predisposing factors in the pathogenesis of acne vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Desferrioxamine treatment of aceruloplasminemia: Long‐term follow‐up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Live imaging of stem cells: answering old questions and raising new ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research DTC pharmaceutical advertising: the debate’s not over
The debate on direct-to-consumer pharmaceutical ads continues, with consumers finding them educational and doctors concerned about their impact on patient relationships and medication understanding.
research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland
Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
research The bright side of fibroblasts: molecular signature and regenerative cues in major organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Influence of feed restriction on the wool proteome: A combined iTRAQ and fiber structural study
Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.
research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
research Electrospun fibrous sponge via short fiber for mimicking 3D ECM
The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.
research Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research The influence of interferon on healthy and diseased skin
Type I interferons play a key role in the development of various skin diseases.
research Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation
Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research The Dynamic Duo: Niche/Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.