6 citations
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July 2018 in “Steroids” Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
13 citations
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November 2017 in “Neurotoxicity research/Neurotoxicity resarch” Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
18 citations
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June 2016 in “PeerJ” Testosterone increases certain kidney protein levels, potentially raising blood pressure.
17 citations
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September 2014 in “PLoS ONE” SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
20 citations
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August 1997 in “PubMed” Increased K+ permeability alone may not promote hair growth.
10 citations
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February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.
5 citations
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May 2022 in “Clinical & Experimental Metastasis” Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.
16 citations
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May 2020 in “Frontiers in pharmacology” Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
4 citations
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January 2010 in “Laboratory Animal Research” Sodium silicate helped mouse hair grow similarly to a known hair growth treatment.
16 citations
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January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
1 citations
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August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
29 citations
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February 2021 in “Cancers” Ion channels play a key role in ovarian cancer growth and treatment resistance.
7 citations
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February 2024 in “The Journal of Physiology” Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
13 citations
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January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
2 citations
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May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
67 citations
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December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
28 citations
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December 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
11 citations
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February 2021 in “Frontiers in Bioengineering and Biotechnology” Small molecule treatments improve the ability of human amniotic fluid stem cells to become different cell types.
140 citations
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February 2014 in “Neuron” Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
68 citations
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January 2013 in “BMC Pharmacology and Toxicology” Glibenclamide slows breast cancer cell growth by stopping cell division.
1 citations
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January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
8 citations
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October 2016 in “Journal of Investigative Dermatology” MR antagonists may improve skin health and wound healing, especially in aging.
August 2018 in “Online journal of neurology and brain disorders” Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
124 citations
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
102 citations
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February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
119 citations
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October 1992 in “Fundamental & Clinical Pharmacology” Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
86 citations
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February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
3 citations
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February 2014 in “Asian Pacific journal of tropical medicine” Wnt5a may slow down hair growth in mice.