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11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro

7 citations , April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology”

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

research External lipid function in ethnic hairs

7 citations , March 2019 in “Journal of cosmetic dermatology”

African hair has the most lipids, while Caucasian hair is more hydrated and stronger.

Experimental and Computational Approaches for Measuring Minoxidil Solubility in Propylene Glycol and Water Mixtures at Different Temperatures

research Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures

7 citations , February 2019 in “Journal of Molecular Liquids”

Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.

research Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5

7 citations , January 2019 in “Pharmaceutical Biology”

Eclipta prostrata helps hair growth and maintains the growth phase by affecting certain growth factors.

research Effect of ethanol Adiantum capillus-veneris extract in experimental models of anxiety and depression

7 citations , January 2019 in “Brazilian Journal of Pharmaceutical Sciences”

Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.

Screening of Euphorbiaceae Plant Extracts for Anti-5α-Reductase Activity

research Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase

7 citations , July 2018 in “Biological & Pharmaceutical Bulletin”

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Interconnected Polymers Technology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions

research Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions

7 citations , July 2018 in “Journal of Functional Biomaterials”

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

research Analysis of Lipids in the Medulla of Japanese Hair and Their Function

7 citations , April 2018 in “Cosmetics”

Lipids in Japanese hair help maintain glossiness and structure.

research Establishment of an evaluation method to detect drug distribution in hair follicles

7 citations , February 2018 in “International Journal of Pharmaceutics”

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers

research Circulating and intraprostatic sex steroid hormonal profiles in relation to male pattern baldness and chest hair density among men diagnosed with localized prostate cancers

7 citations , October 2017 in “The Prostate”

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

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