research GABAAreceptor modulation by neurosteroids in models of temporal lobe epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
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research GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol
Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
research The Effect of 5 -Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Polyamines and hair: a couple in search of perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research Unilateral Gynecomastia Induced by Treatment With 1 mg of Oral Finasteride
Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
research Women's midlife health Reframing menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research Carthami flos: a review of its ethnopharmacology, pharmacology and clinical applications
Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
research The therapeutic use of topical contact sensitizers in benign dermatoses
Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research What′s new in cicatricial alopecia?
New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
research Evaluation of the 5α-reductase inhibitor finasteride on reproduction and gonadal development in medaka, Oryzias latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Elicitor mediated enhancement of wedelolactone in cell suspension culture of Eclipta alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research c-Kit - The Novel Receptor: Physiological Roles, Downstream Signaling and Implications in Cancer
c-Kit is important for heart regeneration and cancer development.
research Polycystic ovary syndrome: diagnosis and management of related infertility
Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Micronutrients for Hair and Nails
Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
research Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms
Natural products might help treat hair greying.
research Phytochemicals as Modulators of Human Endocrine Function: Bridging Traditional Remedies and Hormonal Health
Phytochemicals from plants may help improve hormonal health naturally.
research Exploring Herbal Alternatives to Pharmaceutical Treatments for Polycystic Ovary Syndrome
Herbal supplements like Berberine, Cinnamon, and Fenugreek may be affordable alternatives for managing PCOS.
research Novel Treatment Modalities for Hair Loss
New hair loss treatments show promise, but more research is needed to confirm their effectiveness.
research Antioxidants and Mitochondrial Bioenergetics
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research Genetic Defects of Female Sexual Differentiation
Genetic mutations can affect female sexual development, requiring personalized medical care.
research The Conception and Evaluation of Sexual Health Literature
The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.
research “Spigo nardo”: from the Erbario Estense a possible solution for its taxonomical attribution
Researchers concluded that "spigo nardo" is the Himalayan plant Nardostachys jatamansi, used historically in medicine and cosmetics, now critically endangered.
research Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
research Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides
Polynucleotide injections improved eye wrinkles with few side effects.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.