research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
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research Regulation and Implementation of Pharmaceutical and Other Regulations
Europe strengthened medicine regulations, increased protection against counterfeit drugs, and made it tougher to challenge comparative advertising, while also focusing on patent law enforcement and updating plant protection rules.
research Difficulties Surround Fiber
Eating more protein during weight loss can prevent hair loss caused by not having enough protein.
research Paper 2. Epigallocatechin Gallate and Tannic Acid Based Formulations of Finasteride for Dermal Administration and Chemoembolization
Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
research Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes
research Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata
Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
research Transfollicular drug delivery—Is it a reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Measurement of Skin Permeation/Penetration of Nanoparticles for Their Safety Evaluation
Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
research Modern drug delivery strategies applied to natural active compounds
New drug delivery methods can make natural compounds more effective and stable.
research Preparation of novel polymeric microspheres for controlled release of finasteride
PPCM microspheres allow controlled finasteride release over 24 hours.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations
FOXN1 mutations can cause varying immune and physical issues, with severity influenced by gene activity and possibly other factors.
research Targeted delivery of a poorly water-soluble compound to hair follicles using polymeric nanoparticle suspensions
Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.
research Comparison of the skin penetration of Garcinia mangostana extract in particulate and non-particulate form
Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
research Medical Treatment of Hepatocellular Carcinoma: Any Progress?
As of 1994, treatments for liver cancer had not significantly improved patient survival.
research Hypothalamic DNA methylation in rats with dihydrotestosterone‐induced polycystic ovary syndrome: effects of low‐frequency electro‐acupuncture
Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
research Nanocosmetics: performance enhancement and safety assurance
Nanotechnology improves cosmetics' effectiveness and safety.
research Minoxidil-encapsulated poly(L-lactide-co-glycolide) nanoparticles with hair follicle delivery properties prepared using W/O/W solvent evaporation and sonication
Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
research A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia
Genomic approach finds new possible treatments for hair loss.
research The Interaction of Hair Fibers with Alkali Bromide Solutions
Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.
research Skin care during the menopause period: noninvasive procedures of beauty studies
The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.
research Acne: Diet and acnegenesis
Eating dairy and high glycemic foods may increase the risk of acne.
research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion
Fisetin in fruits and vegetables helps hair growth in mice.
research Targeted photosensitizer delivery: A prospective approach to vitiligo photochemotherapy
The method could improve vitiligo treatment by effectively delivering therapy to hair follicles.
research The Polish version of Skindex-29: psychometric properties of an instrument to measure quality of life in dermatology
The Polish Skindex-29 is a reliable and valid questionnaire for assessing the quality of life in Polish dermatology patients.
research Human hair follicle-derived mesenchymal stem cells improve ovarian function in cyclophosphamide-induced POF mice
Human hair follicle stem cells improve ovarian function in mice with damaged ovaries.
research Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research PNKP is required for maintaining the integrity of progenitor cell populations in adult mice
PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.