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Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

New steroid derivatives show promise as anticancer agents, even against resistant cells.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

A new compound effectively inhibits human 5α-reductase 1.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Compound 1 showed promising anticancer activity.

Four-amino acid part makes enzyme sensitive to finasteride.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

The new formulation greatly improved quercetin absorption in rats.

Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.

A fungal enzyme was used to make compounds more soluble, aiding drug discovery and crop protection.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

Squaric acid dibutylester for alopecia areata can cause benign skin lymphoid growths.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.