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Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

Targeted therapies promoting differentiation could help treat basal cell carcinoma by exhausting cancer stem cells.

Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.

Keratin fibrils in hair form and stop growing at specific points in the follicle.

A method was developed to grow millions of hair cells from a single hair for research and storage.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Cathepsin E is crucial for normal skin cell differentiation and development.

Human hair keratins help nerve regeneration and support Schwann cell activity.

Apoptosis helps shape hair growth and prepares the skin for hair to emerge.

Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.

Keratohyalin and trichohyalin proteins help form and organize skin and hair structures.

Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

A specific type II hair keratin was identified and found in hair cortex and tongue cells.

Understanding intermediate filaments helps explain hair health and related diseases.

Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.

Different keratin proteins are expressed in various epithelial cells at different stages, affecting cell structure and function.

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

Skin organoids can regenerate hair by forming specific cell units with certain signals.

A rare case of severe scalp hair loss and nail issues in keratosis follicularis was observed.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.

K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

Trichoepithelioma and desmoplastic trichoepithelioma have distinct features that can be identified using reflectance confocal microscopy.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.