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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

New compounds may help treat prostate cancer by reducing cell growth.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Alstonia boonei phytochemicals show promise as alternative treatments for BPH with fewer side effects than current drugs.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Certain drugs change freshwater snail shells to a "banana" shape.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

PGD2 stops hair growth and is higher in bald men with AGA.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

New SRD5A2 variants may disrupt protein function, aiding diagnosis and treatment of related disorders.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.