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A 2-year-old girl with a rare vitamin D disorder had rickets and hair loss, but treatment was ineffective due to poor compliance.

Gene variation affects prostate issues and hair loss.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.

A new genetic mutation in the TRPS1 gene causes Trichorhinophalangeal Syndrome, leading to specific hair, dental, and bone issues.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Treatment with 5α-reductase inhibitors is linked to a delay in prostate cancer diagnosis and may affect survival rates.

Targeting the MC-5-HT-HTR2A axis may help treat chronic itching.

EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.

The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.

LPR1 regulates root growth under low phosphate stress independently of SIZ1 in Arabidopsis thaliana.

A new gene mutation linked to Olmsted syndrome may increase cancer risk, suggesting the need for ongoing patient monitoring.

Ceramide synthase 4 is essential for maintaining skin barrier health.

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

A child with skin and heart issues had rare genetic mutations affecting skin and heart cell cohesion.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Compound 15a was effective in inhibiting 5α-reductase.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

5alpha-reductase inhibitors help treat hair loss and prostate issues but may cause sexual side effects.

Armadillo Repeat Only proteins are essential for proper plant growth and response by regulating calcium channels.

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.