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Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

Spt4 and Spt6 are essential for fat cell development.

Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Defective protein folding due to a mutation is key in ANE syndrome.

Scientists created cell lines to study a genetic skin disorder using CRISPR technology.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

A child with skin and tooth symptoms was found to have a genetic mutation causing cardiocutaneous syndrome, leading to heart problems.

The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.

Trichothiodystrophy hair is structurally abnormal with protein and organization issues.

A Pomeranian dog had rickets due to a new gene mutation, leading to severe symptoms and euthanasia.

ACA2 is crucial for root hair growth by controlling calcium levels in cells.

The mineralocorticoid receptor temporarily affects mouse skin development, but the glucocorticoid receptor has a more lasting impact.

GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.

The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

The MDR1 C3435T polymorphism does not significantly affect methotrexate response in rheumatoid arthritis patients.