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Higher CRHR1 levels in AA patients lead to increased inflammation.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.

Male cells need DHT to respond to testosterone, while female cells do not.

Danthron from Rhubarb causes melanoma cells to stop growing and die.

A new genetic variant causes trichothiodystrophy in two brothers, but their mother may carry it without showing symptoms.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

Esrp1 is important for skin health by helping form and maintain the skin barrier.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

A specific gene mutation causes sparse, brittle hair in a family.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

A new ARID1B gene variation causes Coffin-Siris syndrome 1 and early high myopia in a Chinese family.

SLC24A5 shows a clear selective sweep, but no link to UV radiation intensity.

Targeting FGF5 could help treat prostate cancer.

The condition is linked to chromosome 12, but no mutations were found in the known genes.

In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requiring high doses of calcium and vitamin D for treatment.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

Gene variation affects prostate issues and hair loss.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

5α-reduced neurosteroids may help regulate glial cell differentiation.

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.