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Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Finasteride reduces prostate size, improves urination, and slows prostate cancer progression.

Finasteride increases CD8+ T cells in BPH tissues.

Finasteride is made through a series of chemical reactions starting from a specific intermediate compound.

5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

Finasteride changes androgen receptor location in rat epididymis without altering tissue structure.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

Androgens may influence bladder cancer progression by affecting cellular behavior.

ALRV5XR effectively promotes hair regrowth in both men and women through different mechanisms.

The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.

Using 5-α-reductase inhibitors before treatment improves outcomes for patients with metastatic renal cell carcinoma.

Rice bran extract might help prevent hair loss.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

Androgen receptors help prostate cancer cells grow and resist drugs.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.