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New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

MK-386 reduces sebum DHT levels.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Finasteride may help improve certain brain function issues linked to dopamine.

The new compound may be a safer alternative to finasteride for prostate protection.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Ptprq has multiple forms that change during inner ear development.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

ESR2 gene linked to female-pattern hair loss.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.

Spermidine is essential for plant growth and adaptation to stress.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.

Cyclic ADP-ribose helps regulate calcium and signals that promote hair growth in hair follicle cells.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

SHH protein helps nerve regeneration in hypertensive rats.