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A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

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5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

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Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.

Ritlecitinib 50 mg effectively promotes and sustains hair regrowth in alopecia areata patients.

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PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.

SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

A reliable method was developed to measure Tamsulosin and Finasteride in tablets accurately.

S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Ritlecitinib works well and is safe for treating alopecia areata.

Ritlecitinib effectively treats severe Alopecia Areata by reducing harmful immune activity in the skin.

A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

Targeting the MC-5-HT-HTR2A axis may help treat chronic itching.

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Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.