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14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.

Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Most patients tolerated spironolactone for acne and hirsutism despite common side effects like menstrual changes and breast tenderness.

Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.

Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Spironolactone and clascoterone are promising acne treatments with fewer side effects.

Finasteride may cause more sexual side effects than previously thought.

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

Lurasidone is effective for bipolar depression and schizophrenia, but more safety data is needed.

Spironolactone effectively treats female acne with few side effects.

Transdermal fluoxetine is less effective in cats, clomipramine may help with feline alopecia, younger dogs often start fights, dietary changes can reduce cribbing in horses, negative aggression tests in shelter dogs predict good behavior, many older cats show cognitive issues, and fluoxetine or paroxetine can improve canine anxiety.

Finasteride can cause sexual problems and depression in young men.

Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.

5α-Reductase inhibitors can negatively impact sexual function.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.