27 citations
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January 2017 in “Neuropsychopharmacology” The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
May 2025 in “Reactions Weekly”
January 2024 in “Wiadomości Lekarskie” A multidisciplinary approach is crucial for managing Silver-Russell syndrome effectively.
15 citations
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June 2019 in “Journal of Neuroendocrinology” Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.
75 citations
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January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
3 citations
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August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
4 citations
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January 2007 in “Iraqi postgraduate Medical Journal”
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
May 2025 in “Reactions Weekly” May 2018 in “KU ScholarWorks (The University of Kansas)” Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
April 2022 in “Reactions Weekly” 5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
March 2005 in “European Urology Supplements”
10 citations
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May 2018 in “Neuropharmacology” Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
1 citations
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August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
September 2025 in “Reactions Weekly”
May 2011 in “Value in Health” CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.
5 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
January 2011 in “Reactions Weekly”
June 2019 in “Reactions Weekly”
May 2024 in “European urology focus” Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.
February 2026 in “NeuroSci” Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
2 citations
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September 2025 in “Frontiers in Endocrinology” SARMs show promise but need more evidence to prove they're better than traditional androgens.
July 2024 in “Reactions Weekly” August 2011 in “SpringerReference”
August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.