February 2026 in “NeuroSci” Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
3 citations
,
August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
108 citations
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April 2004 in “Medicinal Research Reviews” Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.
1 citations
,
August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
1 citations
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August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
33 citations
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January 2008 in “Journal of Molecular Neuroscience”
9 citations
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April 2020 in “The Journal of Urology” 5α-Reductase inhibitors don't cause depression.
1 citations
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March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
25 citations
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June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
15 citations
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June 2019 in “Journal of Neuroendocrinology” Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.
11 citations
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August 2019 in “BMJ” Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
2 citations
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April 2020 in “Journal of Mind and Medical Sciences” Psychotropic drugs can interact with natural products, affecting their effectiveness and safety.
66 citations
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January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
2 citations
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March 2016 in “Düşünen Adam” Switching from escitalopram to duloxetine improved hair loss.
July 2025 in “Reactions Weekly”
Finasteride and dutasteride are not recommended for feminizing therapy due to limited effectiveness and potential risks.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
63 citations
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March 1998 in “Archives of Dermatology” Antidepressants may improve or resolve scalp dysesthesia in most patients.
5 citations
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May 2011 in “Movement Disorders” Finasteride may help reduce tic severity in male Tourette syndrome patients.
November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.
March 2024 in “Journal of Neuroscience Research” Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
January 2007 in “Edward Elgar eBooks” TSPO might help treat anxiety and depression.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” Post-Finasteride Syndrome causes lasting sexual, mood, and metabolic issues, needing personalized treatment and better informed consent.
January 2014 in “Reactions Weekly” June 2014 in “Reactions Weekly” May 2026 in “Reactions Weekly”