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High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.

Only one K16 gene on chromosome 17 makes a functional keratin protein.

A new mutation in the KRT86 gene causes monilethrix in a Han family.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.

LGD1069 effectively prevents breast tumors in mice without toxicity.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.

Dimethylarsinic acid speeds up skin tumor growth in certain mice.

The hr gene is linked to hair loss in Valle del Belice sheep.

Mutations in the hHb6 gene cause the hair disorder monilethrix.

Cats with abnormal hair had DSG4 gene changes causing hair problems.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

Keratin 16 delays skin maturation and affects skin and hair development in mice.

Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.

The Swedish neonatal screening program effectively detects PKU, galactosaemia, and biotinidase deficiency with low false positives.

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

A new genetic variant causes trichothiodystrophy in two brothers, but their mother may carry it without showing symptoms.

Monoclonal antibodies LT-1, LT-2, and LT-7 help diagnose certain blood cancers.

Trichohyalin, a hair follicle protein, has a part with repeating patterns of 23 amino acids.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Non-coding RNAs may be key in diagnosing and treating rare skin disorders.

Black hairy tongue can be an early sign of graft-versus-host disease after stem cell transplants.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.