research Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle
Cholesterol transport in hair follicles decreases from growth to regression phase.
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research Complex genetic dependencies among growth and neurological phenotypes in healthy children: Towards deciphering developmental mechanisms
Genetic factors influence growth and brain development in children.
research Hominis Placenta facilitates hair re-growth by upregulating cellular proliferation and expression of fibroblast growth factor-7
Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.
research Development of a Doxazosin and Finasteride Transdermal System for Combination Therapy of Benign Prostatic Hyperplasia
Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Microneedling as a successful treatment for alopecia X in two Pomeranian siblings
Microneedling helped two Pomeranian dogs with a hair growth disorder grow back 90% of their fur in 12 weeks, and the results lasted for a year.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Acute sensitivity of the oral mucosa to oncogenic K‐ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
research Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice
Putting α-methylspermidine on mouse skin can start hair growth.
research Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease‐19 (COVID‐19): A scoping review
Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.
research Current status of genus Impatiens: Bioactive compounds and natural pigments with health benefits
Impatiens plants have health-promoting compounds and are used for natural food coloring, but more research is needed to understand their full benefits.
research Hair growth promotion effect of cedrol cream and its dermatopharmacokinetics
Cedrol cream is more effective and safe for promoting hair growth than traditional treatments.
research Polyphenols rich Hibiscus rosa sinensis Linn. petals modulate diabetic stress signalling pathways in streptozotocin-induced experimental diabetic rats
Hibiscus petals improved blood sugar and stress responses in diabetic rats.
research Androgenic alopecia: A counterproductive outcome of the anabolic effect of androgens
Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
research Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
Solanum nigrum shows promise for treating COVID-19 and its complications, but more research is needed.
research Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway
The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities
Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.
research Hibiscus rosa sinensis Linn. Petals Modulates Glycogen Metabolism and Glucose Homeostasis Signalling Pathway in Streptozotocin-Induced Experimental Diabetes
Hibiscus petals helped control blood sugar and improve liver and pancreas health in diabetic rats.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
Low ERCC3 gene activity is linked to non-pigmented hair growth.
research Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression
The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
research Fundamental studies on the interaction between moisture and textiles. Part X. Moisture sorption properties of wool and hair fibers.
Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
research Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing
The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.
research Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
research Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase
Compound 15a was effective in inhibiting 5α-reductase.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research Specific interpretation of hair concentrations in 2 fatal metformin intoxication cases
Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.